Microbiology & Immunology- Biochemistry-BSC-Nagpur-Summer-2018

Bachelor of Science (B.Sc.) Semester—2 Examination
BIO-CHEMISTRY (Microbiology & Immunology)

Optional Paper—1
Time : 3 Hours
Maximum Marks : 50

N.B. :— (1) All questions are compulsory and carry equal marks.
(2) Draw well labelled diagram wherever necessary.

1. Give a detailed account of the classification of bacteria on the basis of their nutritional requirements.
[10M]

OR

What is meant by a pure culture ? Describe the pour plate and streak plate methods for obtaining pure
culture. [10M]

2. Define the term microbial control. Describe osmotic pressure, surface tension and filtration as methods
for controlling growth of microorganisms. [10M]

OR

Explain the role of following as chemotherapeutic agent :

(a) Antibiotics

(b) Sulphonamides. [10M]

3. Write notes on the following organs of the immune system :

(a) Thymus[2½M]

(b) Bone marrow [2½M]

(c) Lymph nodes [2½M]

(d) Spleen. [2½M]

OR

What are antibodies ? Describe in detail the basic structure of IgG molecule. [10M]

4. What are monoclonal antibodies ? Discuss the method of preparation and their applications.
[10M]

OR

Briefly describe :

(a) Cellular immunity [5M]

(b) Humoral immunity. [5M]

5. Answer any TEN of the following :

(i) What are phototrophs ?[1M]

(ii) Name the carbon source in nutrient broth.[1M]

(iii) What is meant by an enrichment culture medium ?[1M]

(iv) Define a sanitizer.[1M]

(v) Give one point of difference between a microbiocidal and a microbiostatic agent.[1M]

(vi) Name any one heavy metal involved in oligodynamic action.[1M]

(vii) What are macrophages ?[1M]

(viii) Give the full form of MALT.[1M]

(ix) Define a hapten.[1M]

(x) What is full form of MHC ?[1M]

(xi) Define the term clonal selection.[1M]

(xii) What are memory cells ? [1M]