Question: 137 Which of the following statements are correct about Klinefelter’s Syndrome?
A. This disorder was first described by Langdon Down (1866).
B. Such an individual has overall masculine development. However, the feminine development is also expressed.
C. The affected individual is short statured.
D. Physical, psychomotor and mental development is retarded.
E. Such individuals are sterile.
Choose the correct answer from the options given below :
(1) B and E only
(2) A and E only
(3) A and B only
(4) C and D only
Answer: Option (1)
Explanation:
Klinefelter’s syndrome is a chromosomal disorder caused due to the presence of an extra X chromosome in males, commonly with the karyotype 47, XXY.
This condition was described by Harry Klinefelter and not by Langdon Down,
so statement A is incorrect.
Affected individuals show overall masculine development but also exhibit some feminine
characteristics such as gynecomastia, so statement B is correct.
Individuals with Klinefelter’s syndrome are usually tall, not short statured,
so statement C is incorrect.
Mental retardation is not a typical feature; most individuals have normal intelligence,
so statement D is incorrect.
Such individuals are generally sterile due to underdeveloped testes and low sperm production,
so statement E is correct.
Therefore, the correct statements are B and E only.
Hence, Option (1) is the correct answer.