Question: 141 Broad palm with single palm crease is visible in a person suffering from-
(1) Klinefelter’s syndrome
(2) Thalassemia
(3) Down’s syndrome
(4) Turner’s syndrome
Answer: Option (3)
Explanation:
Down’s syndrome is a chromosomal disorder caused due to the presence of an extra copy of chromosome 21, resulting in trisomy 21.
Individuals affected by this condition show several characteristic physical features.
One of the most common and distinctive features of Down’s syndrome is a broad palm with a single transverse palmar crease, also known as a simian crease.
Klinefelter’s syndrome is characterized by the presence of an extra X chromosome in males and mainly affects sexual development.
Thalassemia is a genetic blood disorder affecting hemoglobin synthesis and does not cause palm crease abnormalities.
Turner’s syndrome occurs due to the absence of one X chromosome in females and is associated with short stature and reproductive abnormalities, not a single palm crease.
Hence, the correct answer is Down’s syndrome.