Question: 147 Which of the following is not a cloning vector?
(1) pBR322
(2) Probe
(3) BAC
(4) YAC
Answer: Option (2)
Explanation:
A cloning vector is a DNA molecule used to carry foreign DNA into a host cell and replicate it.
pBR322 is a plasmid vector commonly used in genetic engineering and hence is a cloning vector.
BAC stands for bacterial artificial chromosome and is used as a cloning vector for large DNA fragments.
YAC stands for yeast artificial chromosome and is also used as a cloning vector for very large DNA inserts.
A probe is a labeled DNA or RNA fragment used to detect the presence of a complementary sequence and does not function in replication or transfer of DNA.
Therefore, probe is not a cloning vector.