Question: 162 In which blood corpuscles, the HIV undergoes replication and produces progeny viruses?
(1) Basophils
(2) Eosinophils
(3) \mathrm{T}_{\mathrm{H}} cells
(4) B-lymphocytes
Answer: Option (3)
Explanation:
Human Immunodeficiency Virus (HIV) primarily targets \mathrm{T}_{\mathrm{H}} cells,
also known as helper T-lymphocytes.
These cells possess CD4 receptors on their surface, which allow the virus to attach and enter the cell.
Inside the \mathrm{T}_{\mathrm{H}} cells, HIV replicates and produces progeny viruses.
The destruction of these cells weakens the immune system and leads to Acquired Immunodeficiency Syndrome (AIDS).
Basophils, eosinophils and B-lymphocytes are not the primary sites of HIV replication.
Hence, HIV undergoes replication in \mathrm{T}_{\mathrm{H}} cells.