Question: 139: If a geneticist uses the blind approach for sequencing the whole genome of an organism, followed by assignment of function to different segments, the methodology adopted by him is called as :
(1) Expressed sequence tags
(2) Bioinformatics
(3) Sequence annotation
(4) Gene mapping
Answer: Option (3)
Explanation:
In the blind approach, the entire genome of an organism is sequenced
without prior knowledge of gene locations.
After sequencing, different DNA segments are analyzed to identify genes and assign functions to them.
This process of identifying coding regions, regulatory sequences,
and determining their biological functions is known as sequence annotation.
Expressed sequence tags involve sequencing only expressed genes and not the whole genome.
Bioinformatics refers to the use of computational tools to analyze biological data, not a specific sequencing methodology.
Gene mapping involves locating genes on chromosomes,
not assigning functions after whole-genome sequencing.
Therefore, the correct answer is Option (3).