Question: 156: Gout is a type of disorder which leads to:
(1) Inflammation of joints due to accumulation of uric acid crystals
(2) Weakening of bones due to decreased bone mass
(3) Inflammation of joints due to cartilage degeneration
(4) Weakening of bones due to low calcium level
Answer: Option (1)
Explanation:
Gout is a metabolic disorder caused by excess accumulation of uric acid in the blood, a condition known as hyperuricemia.
When the concentration of uric acid becomes high, it crystallizes and gets deposited in the joints, especially in the toes, ankles, and knees.
The deposition of uric acid crystals triggers an inflammatory response, leading to severe joint pain, swelling, and redness.
Weakening of bones due to decreased bone mass is characteristic of osteoporosis.
Inflammation due to cartilage degeneration is seen in osteoarthritis, and low calcium levels can lead to conditions like rickets or osteomalacia.
Therefore, gout leads to inflammation of joints due to accumulation of uric acid crystals.